The Pleasure—And Pain—Of Horseradish

April 30, 2025 Morehouse

The Pleasure—And Pain—Of Horseradish

If you’ve ever had horseradish, you know how unique the flavor and experience is. Did you know that this experience could be explained by science? Let’s take a closer look at this interesting root known as horseradish. 

Is horseradish healthy? Best prepared horseradish in Los Angeles, CA and Santa Ana, CA.The Science Behind Horseradish

The key compound in horseradish responsible for its pungency is sinigrin, a glucosinolate stored in the plant’s roots. When the plant tissue is damaged—such as during grating or chopping into small pieces—sinigrin interacts with the enzyme myrosinase, leading to the production of allyl isothiocyanate. This compound is a lachrymator, meaning it can cause tearing, eye pain, and nausea upon inhalation. These effects are mediated by the TRPA1 receptor, which is also activated by other irritants like capsaicin from chili peppers.

So that’s a whole lot of science, but it’s quite interesting when we consider where else these compounds are found elsewhere. While horseradish and the chemicals found in the root aren’t in tear gas, the compound lachrymator is. This alone can explain why sometimes that pungent bite of horseradish can put you back on your heels.

The Pleasure Behind Horseradish

Now that we know the science behind why horseradish packs a pungent punch let’s look at why people love this condiment. There are quite a few reasons that contribute to why people continue to add horseradish to classic recipes such as cocktail sauce, sandwiches, and even Bloody Mary’s! Below are some reasons:

  • Chemical Kick (TRPA1 activation): Directly related to the chemical makeup explained before, the sharp, pungent sensation comes from allyl isothiocyanate, which activates the TRPA1 receptors (also called the “wasabi receptor”). This creates a burning, sinus-clearing rush—like a controlled irritation—that some people find exhilarating, much like the burn of chili peppers or the sting of mustard.
  • Endorphin Rush: That mild pain or intense sensation can trigger a release of endorphins—the body’s natural feel-good chemicals—creating a quick high or sense of euphoria. Sometimes people actively crave spicy food, and a byproduct of this is a potentially improved mood, too!
  • Flavor Enhancement: Horseradish cuts through fatty, rich foods (like roast beef or sausages), enhancing the overall flavor profile. It adds brightness, bite, and balance.
  • Cultural/Emotional Connection: For many, horseradish is tied to tradition—Jewish Passover seders, Eastern European dishes, or family recipes. 

So, horseradish not only packs a powerful and fun flavor, but it’s also the whole sensory and emotional experience that makes horseradish enjoyable and memorable. Science explains why this occurs, but horseradish may not be an immediate love for everyone. Sometimes, it has to complement the proper meal or drink to make a sceptic a lover of the pungent condiment. 

Products with all-natural ingredients in Los Angeles, CA and Anaheim, CA.Morehouse Delivers Quality Products

Since 1989, Morehouse has been crafting the highest-quality horseradish and mustard for our consumers near and far. We have been family-owned for five generations and care about customer satisfaction and quality products over all else. Our varieties of mustard and horseradish satisfy both classic and innovative dishes. Find us in your local supermarket or proudly displayed at restaurants in your area.

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